Advanced Organic Chemistry

Advanced Organic Chemistry
Physical aspects of organic chemistry; mechanisms, reaction intermediates, bonding, stereochemical and stereoelectronic effects, molecular orbital theory, Lewis acidity and basicity.
 Hours3.0 Credit, 3.0 Lecture, 0.0 Lab
 PrerequisitesCHEM 352M; or CHEM 352; Chem 462 and 463 (or Chem 468).
 ProgramsContaining CHEM 552
Course Outcomes

Outcome 1

Predict relative energies and locations of frontier molecular orbitals for organic molecules of intermediate complexity using linear combinations of atomic orbitals and hybridized orbital approaches.

Outcome 2

Perform calculations using ab initio, semi-empirical, density functional, and molecular mechanics approaches to predict energies and structures of ground and transition states.

Outcome 3

Use reaction kinetics, linear free energy relationships, isotope labeling, stereo-electronic effects and stereochemical outcomes to determine reaction mechanisms.

Outcome 4

Predict reaction mechanisms of major classes of organic reactions, including substitutions, eliminations, additions and radical reactions.

Outcome 5

Recognize the impact of non-covalent interactions in complex systems and reaction mechanisms.